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Methemoglobinemia due to prilocaine during neonatal circumcision: a case report [J Behcet Uz Child Hosp]
J Behcet Uz Child Hosp. 2015; 5(1): 65-68 | DOI: 10.5222/buchd.2015.065  

Methemoglobinemia due to prilocaine during neonatal circumcision: a case report

Özkan İlhan, Esra Arun Özer, Senem Alkan, Sinem Akbay, Berat Kanar, Şeyma Memur, Mustafa Mansur Tatlı
Department Of Neonatology, Tepecik Training And Research Hospital, Yenişehir, İzmir, Turkey.

Methemoglobinemia, which may cause cyanosis in the neonatal period, is a rare hematological disorder. Methemoglobinemia may occur in congenital and acquired conditions. Drugs are the most reason of methemoglobinemia in newborns. It is reported that prilocaine, is widely used as a local anesthetic, may causes acquired methemoglobinemia in the neonatal period. A 10-hour-old newborn, who became cyanotic after applying prilocaine as a local anesthetic before the circumcision, was diagnosed with methemoglobinemia and successfully treated with intravenous ascorbic acid therapy. In this study, methemoglobinemia, which is a rare clinical condition, and its treatment are discussed and presented with the literature.

Keywords: Ascorbic acid, methemoglobinemia, prilocaine, circumcision, newborn


Sünnet sırasında prilokain kullanımına bağlı methemoglobinemi: Bir olgu sunumu

Özkan İlhan, Esra Arun Özer, Senem Alkan, Sinem Akbay, Berat Kanar, Şeyma Memur, Mustafa Mansur Tatlı
Tepecik Eğitim Ve Araştırma Hastanesi Neonatoloji Kliniği, İzmir.

Methemoglobinemi yenidoğan döneminde siyanoza neden olabilen, nadir bir hematolojik hastalıktır. Konjenital ya da edinsel olmak üzere iki tipi bulunan methemoglobinemi yenidoğan döneminde en sık ilaç reaksiyonu olarak ortaya çıkmaktadır. Lokal anestezik olarak yaygın kullanılan prilokainin, yenidoğan bebeklerde edinsel methemoglobinemiye yol açabildiği bildirilmektedir. Sünnet öncesi lokal anestezik olarak prilokain uygulanan ve siyanoz gelişen 10 saatlik bir yenidoğan bebek, methemoglobinemi tanısı konularak intravenöz askorbik asit tedavisi ile başarıyla tedavi edilmiştir. Nadir görülen bir klinik durum olan methemoglobinemi ve tedavisi literatür eşliğinde tartışılarak sunulmuştur.

Anahtar Kelimeler: Askorbik asit, methemoglobinemi, prilokain, sünnet, yenidoğan


Özkan İlhan, Esra Arun Özer, Senem Alkan, Sinem Akbay, Berat Kanar, Şeyma Memur, Mustafa Mansur Tatlı. Methemoglobinemia due to prilocaine during neonatal circumcision: a case report. J Behcet Uz Child Hosp. 2015; 5(1): 65-68

Corresponding Author: Özkan İlhan, Türkiye


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