Abstract

Mechanical ventilation is a common therapy to treat infants with respiratory insufficiency. Advances in pulmonary care such as surfactant replacement therapy and improved mechanical ventilation have reduced the mortality of infants, but important respiratory morbidities continue to affect infant. Complications of mechanical ventilation include volutrauma, extrapulmonary air leak syndromes, traumatic injury to large airways, and endotracheal tube complications. In this report we have presented two cases with lung complications due to repeated surfactant therapy and had mechanical ventilation support.