Histopathological frequency of Helicobacter pylori in children between 1-18 ages in the Erzurum province

INTRODUCTION

The purpose of this study is to investigate the frequency of Helicobacter pylori (HP) in the Erzurum province in the pediatric age group’s upper gastrointestinal (GI) endoscopy.

METHODS

In July 2014-May 2015 period, 59 patients which were performed upper GI endoscopy in our hospital and were taken antral biopsies, between 1-18 years old, included in the study and analyzed retrospectively. Antrum biopsies stained with hematoxylin-eosin and modified Giemsa and evaluated by light microscopy. Mononuclear cell infiltration, neutrophil infiltration, atrophy, intestinal metaplasia, HP existence examined and classified as negative (0), mild (+1), moderate (+2), severe (+3) according to the Sydney system.

RESULTS

38 of our patients were female (64.4%) and 21 of them were male (35.6%) and the mean age was 11.84 ± 4.88 years. HP was found in 36 cases (61.01%) in varying degrees. HP rates in male patients 66.66% (14/21), 57.89% in females (22/38) in terms of gender. The frequencies of HP 57.14%, 56.25%, 63.88%, respectively, in the age groups 1-5 years, 6-10 years, 11-18 years. %33.33 of patients had mild, %52.78 had moderate, %13.89 had severe positivity for HP. Mononuclear cell infiltration in varying degrees were seen in all of 36 HP positive patients and neutrophil infiltration in varying degrees were seen 33 of them.

DISCUSSION AND CONCLUSION

In the Erzurum province the frequency of HP in the pediatric age group’s endoscopic biopsies is 61.01%. In 1-5 years children HP frequency was detected as 57.14%. This rate is higher than the studies that were made in our country's west and the western countries.