Abstract
OBJECTIVE
Henoch-Schönlein purpura (HSP) is the most common systemic vasculitis in children. The aim of this study was to investigate the clinical and demographic features and laboratory finding of disease in our patients with Henoch-Schönlein purpura.
METHODS
Sixty-two patients with Henoch-Schönlein purpura who were diagnosed and observed in our department of pediatrics between January 2005 and December 2010 were retrospectively evaluated.
RESULTS
Thirty eight (55%) of the patients were male and 24 (45%) were female. Mean age of the patients was 6.9 years (2-14 years). The distribution of cases according to the seasons: autumn 27.5% (n = 17), winter 29% (n = 18), spring 25.8% (n = 16), summer 17.7% (n = 11). All patients had purpuric skin lesions 100% (n=62), 67.7% (n=42) had joint, 37.1% (n=23) had gastrointestinal system, 12.9% (n=8) had renal and 4.8% (n=3) had scrotal involvement. Hematuria was detected in 8% (n=8), proteinuria in 3.2% (n=2), hematuria with proteinuria in 1.6% (n=1). Renal biopsy was not needed as there was no persistent hematuria and proteinuria. Nine (%14.5) patients had anemia, 11 (%17.7) patients had leukocytosis, 23 (%37.1) patients had thrombocytosis, 34 (%54.8) patients had increased erythrocyte sedimentation rate and 39 (%62.9) patients had positive CRP.
CONCLUSION
Henoch-Schönlein purpura in a wide range of age and be detected in all seasons. The disease is usually self-limiting and the prognosis is good.
Keywords: Henoch-Schönlein purpura, vasculitis, child
